NAD+ vs. Myers' Cocktail: Which IV Drip Is Right for You?
A clear comparison of the two most-asked-about IV drips — what each does, what they cost, and how to choose.
A Myers' Cocktail is a classic vitamin-and-mineral drip (magnesium, calcium, B vitamins, and vitamin C) used for everyday energy, immune support, and general wellness — it's quick, affordable, and a great first drip. NAD+ is a specialized coenzyme infusion used for energy, mental clarity, recovery, and longevity — it costs several times more and takes much longer to infuse. Choose a Myers' for an accessible wellness boost; choose NAD+ if you're specifically after the cellular-energy and longevity effects and don't mind the time and price.
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What each one is
The Myers' Cocktail is the original wellness IV — a balanced blend of magnesium, calcium, a B-complex with extra B12, and vitamin C in saline. It's a generalist drip: people use it for fatigue, run-down immunity, migraines, and a routine feel-better top-up.
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme central to how cells make energy and repair themselves. An NAD+ drip delivers a large dose directly into the bloodstream, and people use it for sustained energy, focus, athletic and addiction recovery, and 'healthy aging.'
Time, cost, and how they feel
Time and price are the biggest practical differences. A Myers' Cocktail runs about 30–45 minutes and typically costs $130–$200. NAD+ must be infused slowly to avoid discomfort, so a meaningful dose takes two to four hours and costs roughly $250 for a small dose up to $800–$1,000 for 1,000mg.
They feel different, too: a Myers' gives a hydration-and-vitamin lift many people notice the same day, while NAD+ users often describe a deeper, more sustained boost in energy and clarity over the following days. The NAD+ evidence is still early, so treat its longevity claims as promising rather than proven.
How to choose
Pick a Myers' Cocktail if you want an affordable, quick, well-rounded wellness drip — it's the sensible default and a great starting point if you're new to IV therapy. Pick NAD+ if you're specifically chasing the cellular-energy, focus, or longevity effects and you're comfortable with the longer session and higher cost.
Some people do both for different reasons: a Myers' as a regular top-up, NAD+ occasionally for a bigger reset. Whichever you choose, use a licensed provider with real medical oversight — dose and drip-rate control matter more with NAD+.
Frequently asked
Is NAD+ better than a Myers' Cocktail?+
Neither is universally 'better' — they do different things. A Myers' Cocktail is a quick, affordable all-purpose wellness drip; NAD+ is a longer, pricier infusion aimed at cellular energy, focus, and longevity. The right one depends on your goal, budget, and time.
Can you combine NAD+ and a Myers' Cocktail?+
Some clinics offer them together or in sequence, and many people alternate — a Myers' as a routine top-up and NAD+ occasionally. Ask your provider what makes sense for your goals; they'll tailor dosing and timing.
This guide is informational — independently researched and fact-checked against published clinical sources. It is not a substitute for personalized medical advice.